We further investigated the conformational properties of these analogs by 1D and 2D ~1H NMR spectroscopy and molecular modeling.
我们还通过1D和2D~1HNMR谱和分子动力学模拟进一步研究这些类似物的构象特性。
1·Effects of perturbing various model parameters on the equilibriums between native-like states with other conformational states were considered.
我们考虑扰动不同力场参数对天然态和其它构象态之间平衡的影响。
2·This suggests that conformational integrity of aminoacylase appears to be essential for its catalytic activity.
这表明酶基酰化酶构象的完整性是酶具有催化活力的基础。
3·Due to their unique structures and properties, synthetic polypeptides recently have been studied widely in the field of protein simulation, macromolecular conformational study and biomedicine.
由于其独特的结构和性能，近年来在蛋白质结构模拟、分子链构象研究、生物医学等领域被广泛地加以研究。
4·Because of the high chemical activity, the structural complexity and the conformational flexibility of enzymes, it is difficult to study of the interaction of rare earth ions with enzymes.
其主要原因是由于这些酶具有高化学活性、结构复杂性、构象易变性等特点，使研究这些酶与稀土离子相互作用比较困难。
5·We use a uniformly rotating dipole, which represent the inner freedom, to describe conformational changes.
用一个匀速转动的偶极子来描述马达的构象变化，考虑了马达的内部自由度。