point mutation
点突变：一种基因突变
常用释义
英式发音
美式发音
基本释义
- 点突变：一种基因突变，涉及到单个核苷酸碱基的替代、添加或删除。
例句
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1·No p16 gene point mutation was detected.所有标本未检出点突变。
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2·Applying RNase Protection assay, the point mutation in the RB gene was observed.运用核酸酶保护试验观察rb基因的点突变现象。
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3·Missense mutation a point mutation that causes a change in one amino acid of a protein.错义突变引起蛋白质中一个氨基酸变化的点突变。
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4·Solid-phase proofreading PCR and silver staining of colloidal gold were applied to detect the point mutation.对固相校读PCR以及纳米金-银染法检测信号进行了初步摸索；
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5·Based on the number of restriction enzyme detecting RFLPs, most of mutations were attributed to point mutation.根据揭示多态性的限制性内切酶的数量可将产生的突变大多归为点突变。
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6·However, several problems, such as the conservation and distribution of point mutation, remain to be clarified.但仍有一些问题，如突变的保守性和分布，需要进一步研究、阐明。
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7·Twenty cases(20/31) were selected randomly for DNA sequencing. No point mutation of ABCB4 gene exon 23 were detected.随机挑选20例标本测定外显子23的DNA序列，未发现点突变。
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8·This single - point mutation engages the leg - making apparatus of the embryo fly to build a leg where its antenna should be.这个单点突变搅乱了果蝇胚胎的足肢生成装置，在原本应该是触角的地方生出一条腿来。
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9·AIM: To investigate the relationship between the point mutation of ABCB4 gene and intrahepatic cholestasis of pregnancy (ICP).目的：探讨ABCB 4基因点突变与妊娠期肝内胆汁淤积症(ICP)发病的关系。
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10·In BCR-ABL fusion gene negative myeloproliferative diseases, the discovery of JAK2V617F point mutation is an important landmark.在BCR - ABL阴性的骨髓增殖性疾病的发病机制中，JAK2V 617 F点突变的发现是一个重大的突破。